Efficient removal performance of small molecules with minimum albumin loss
The FDX-series are suited for standard hemodialysis.
Because it is a type with a low albumin leakage, it can be used from the introduction of dialysis.
The precisely measured amount of PVP supports the blood compatibility and filtration properties.
Dialyzers for high -flux dialysis and hemodiafiltration
🔹 Optional endotoxin-retentive performance
🔹 No PVP elution
🔹 Optimal follow fibers design
Optional endotoxin-retentive performance
Polyester polymer alloy (PEPA) membrane is synthetic polymer membrane and consists of two polymers –polyethersulfone (PES) and polyarylate (PAR).
PEPA membrane utilizes a polymer blend technology and creates a multicomponent polymer with strong points of each polymer.
The specially developed asymmetric 3-layer structure of the PEPA® – membrane provides protection against endotoxins and their fragments.
Specially developed 3-layer structure of the PEPA membrane
[1] Dialysate side: skin layer; endotoxin block
[2] Main body: porous layer; mechanical strength
[3] Blood side: skin layer; solute separation
No PVP elution
In FD series, the appropriate pore size of PEPA® membrane can be controlled easily by a mixture ratio of two polymers, so the use of a hydrophilizing agent is low as necessary for hydrophilization purpose only.
With this optimum hydrophilization technology, there is no PVP elution in the FD series.
Optimal follow fibers design
The optimized inner diameter of the follow fibers ensures a low blood side pressure drop,
and the membrane thickness of 30 μm provides good diffusion properties.
NIKKISO original PEPA®-membrane
| Membrane thickness | 30μm |
| Hollow fiber inner diameter | 210μm |
| Membrane material | PEPA(Polyester - Polymer alloy) |
| Housing material | Polycarbonate |
| Sealant material | Polyurethane |
| Sterilization | Gamma rays |
PEPA Dialyzer FDX
| Model | Surface area [㎡] | Volume [mL] | UFR*1 [mL/hr/mmHg] | Clearance[mL/min]*2 | ||||
|---|---|---|---|---|---|---|---|---|
| Urea | Creatinine | Phosphate | VitaminB12 | |||||
| FDX-08 | 0.8 | 50 | 36 | 169 | 153 | 143 | 97 | |
| FDX-10 | 1.0 | 61 | 36 | 180 | 168 | 155 | 112 | |
| FDX-12 | 1.2 | 74 | 47 | 186 | 176 | 168 | 125 | |
| FDX-15 | 1.5 | 92 | 52 | 190 | 183 | 177 | 136 | |
| FDX-18 | 1.8 | 111 | 57 | 192 | 186 | 180 | 142 | |
| FDX-21 | 2.1 | 129 | 64 | 193 | 187 | 181 | 145 | |
*1. QB 200mL/min, TMP 50 mmHg with bovine blood (Ht: 32%, TP: 6.0g/dL) (ISO8637-1:2017)
*2. QB 200mL/min, QD 500mL/min, QF 0mL/min (ISO8637-1:2017)
Disclaimer:
* Product appearance and specifications are subject to change without prior notice.
* Photographs of the product may appear differently due to variations in printing or display conditions.
* Specifications may vary depending on local regulations and registration status. Please contact your local distributor for details.
* Always read the accompanying operation manual before use.
